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1

Efficient Access to Oseltamivir Phosphate (Tamiflu) via the O-Trimesylate of Shikimic Acid Ethyl Ester

Martin Karpf, René Trussardi

Journal:

Angewandte Chemie International Edition

Year:

2009

Language:

english

File:

PDF, 326 KB

english, 2009

2

Effizienter Zugang zu Oseltamivirphosphat (Tamiflu) über das O-Trimesylat von Shikimisäureethylester

Martin Karpf, René Trussardi

Journal:

Angewandte Chemie

Year:

2009

Language:

german

File:

PDF, 315 KB

german, 2009

3

Investigation of the Cyclopentenone Formation via the α-Alkynone Cyclisation: Synthesis of the Acorone Intermediate 8-Methylspiro[4.5]deca-3,7-dien-2-one

John Ackroyd, Martin Karpf, André S. Dreiding

Journal:

Helvetica Chimica Acta

Year:

1985

Language:

english

File:

PDF, 501 KB

english, 1985

4

Ammonolysis with supercritical NH3

Shaoning Wang, Martin Karpf, Frank Kienzle

Journal:

The Journal of Supercritical Fluids

Year:

1999

Language:

english

File:

PDF, 211 KB

english, 1999

5

Congenital generalized cystic lymphangiomatosis diagnosed by prenatal ultrasound

Martin C. H. Haeusler, Hans M. H. Hofmann, Werner Hoenigl, Eva F. Karpf, W. Rosenkranz

Journal:

Prenatal Diagnosis

Year:

1990

Language:

english

File:

PDF, 343 KB

english, 1990

6

Organische Synthese bei hohen Temperaturen: Gasphasen-Strömungsthermolyse

Dr. Martin Karpf

Journal:

Angewandte Chemie

Year:

1986

Language:

german

File:

PDF, 1.31 MB

german, 1986

7

Organic Synthesis at High Temperatures. Gas-Phase Flow Thermolysis [New Synthetic Methods (57)]

Priv.-Doz. Dr. Martin Karpf

Journal:

Angewandte Chemie International Edition

Year:

1986

Language:

english

File:

PDF, 1.34 MB

english, 1986

8

ChemInform Abstract: New, Azide-Free Transformation of Epoxides into 1,2-Diamino Compounds: Synthesis of the Antiinfluenza Neuraminidase Inhibitor Oseltamivir Phosphate (Tamiflu).

Martin Karpf, Rene Trussardi

Journal:

Year:

2001

File:

PDF, 38 KB

2001

9

The Synthetic Development of the Antiinfluenza Neuraminidase Inhibitor Oseltamivir Phosphate (Tamiflu): A Challenge for Synthesis & Process Research

Stefan Abrecht, Peter Harrington, Hans Iding, Martin Karpf, Rene Trussardi, Beat Wirz, Ulrich Zutter

Journal:

Year:

2005

File:

PDF, 8 KB

2005

10

Anwendung von Ringerweiterungen zur Herstellung von rac-Muscon und Exalton®

Martin Karpf, André S. Dreiding

Journal:

Helvetica Chimica Acta

Year:

1975

File:

PDF, 1.81 MB

1975

11

Sind Zwischenstufen mit pentakoordinierten C-Atomen bei aliphatischen SN2-Reaktionen nachgewiesen??

Tiziana Vergnani, Martin Karpf, Lienhard Hoesch, André S. Dreiding

Journal:

Helvetica Chimica Acta

Year:

1975

File:

PDF, 817 KB

1975

12

Eine Synthese von Bicyclo[10.3.0]pentadec-1(12)-en-13-on und seinem 14-Methylderivat

Martin Karpf, André S. Dreiding

Journal:

Helvetica Chimica Acta

Year:

1976

Language:

german

File:

PDF, 511 KB

german, 1976

13

Azimine. I. Bildung und Stereoisomerie von 2, 3-Diaryl- und 2, 3-Dialkyl-1-phthalimido-aziminen

Lienhard Hoesch, Martin Karpf, Esra Dunkelblum, André S. Dreiding

Journal:

Helvetica Chimica Acta

Year:

1977

Language:

english

File:

PDF, 964 KB

english, 1977

14

Azimine. II. Synthese und thermische Fragmentierung von cis- und trans-2,3-Diphenyl-1-phthalimido-2,3-di[15N]-azimin

Christian Leuenberger, Martin Karpf, Lienhard Hoesch, André S. Dreiding

Journal:

Helvetica Chimica Acta

Year:

1977

File:

PDF, 740 KB

1977

15

Synthesen und Thermolysen von 1-Alkinyl-2-methyl-1,2-epoxy-cycloalkanen. - Versuche zur Ringerweiterung um drei Kohlenstoffatome

Martin Karpf, André S. Dreiding

Journal:

Helvetica Chimica Acta

Year:

1977

File:

PDF, 991 KB

1977

16

Umwandlung der diastereomeren 12- und 6-gliedrigen 1-Acetyl-2-methyl-1-cycloalkanole in 1-Äthinyl-2-methyl-1-cycloalkene

Martin Karpf, David Walton, André S. Dreiding

Journal:

Helvetica Chimica Acta

Year:

1978

File:

PDF, 923 KB

1978

17

Thermische Cyclisierung von α-Alkinonen zu 2-Cyclopentenonen

Martin Karpf, André S. Dreiding

Journal:

Helvetica Chimica Acta

Year:

1979

File:

PDF, 833 KB

1979

18

Anwendung der α-Alkinon-Cyclisierung: Synthese von rac-Modhephen

Martin Karpf, André S. Dreiding

Journal:

Helvetica Chimica Acta

Year:

1981

File:

PDF, 710 KB

1981

19

Specificities of the α-Alkynone-Cyclization

Martin Karpf, Joan Huguet, André S. Dreiding

Journal:

Helvetica Chimica Acta

Year:

1982

Language:

english

File:

PDF, 862 KB

english, 1982

20

Consecutive Application of the α-Alkynone Cyclization: Total Synthesis of (±)-Δ9(12)-Capnellene

Joan Huguet, Martin Karpf, André S. Dreiding

Journal:

Helvetica Chimica Acta

Year:

1982

Language:

english

File:

PDF, 576 KB

english, 1982

21

On the Mechanism of the α-Alkynone Cyclization: A Theoretical Study

José Kaneti, Martin Karpf, André S. Dreiding

Journal:

Helvetica Chimica Acta

Year:

1982

Language:

english

File:

PDF, 435 KB

english, 1982

22

Anwendung der α-Alkinon-Cyclisierung: Totalsynthese von (±)-Alben

Giuseppe G. G. Manzardo, Martin Karpf, André S. Dreiding

Journal:

Helvetica Chimica Acta

Year:

1983

Language:

german

File:

PDF, 370 KB

german, 1983

23

Zum Mechanismus der α-Alkinon-Cyclisierung: Synthese und Thermolyse von 1-(1-Methylcyclopentyl)[3-13C]prop-2-inon

Manuel Koller, Martin Karpf, André S. Dreiding

Journal:

Helvetica Chimica Acta

Year:

1983

File:

PDF, 618 KB

1983

24

Die Acylierung von Acetylenen mit β, γ-ungesättigten Säurechloriden. Eine neue Synthese von 5-Cyclopentenonen

Journal:

Helvetica Chimica Acta

Year:

1984

File:

PDF, 927 KB

1984

25

Total Synthesis of (±)-Clovene. On the Stereoelectronic Requirements of the α-Alkynone Cyclisation

John Ackroyd, Martin Karpf, André S. Dreiding

Journal:

Helvetica Chimica Acta

Year:

1984

Language:

english

File:

PDF, 586 KB

english, 1984

26

Die Gasphasen-Flussthermolyse von 1-Isobutenyl- und 2-Methylphenyl-alkinyl-ketonen. Eine Synthese von Methylenomycin B

Manuel Koller, Martin Karpf, André S. Dreiding

Journal:

Helvetica Chimica Acta

Year:

1986

File:

PDF, 1.42 MB

1986

27

Formale Totalsynthese von (±)-Isocomen durch Anwendung der α-Alkinon-Cyclisierung

Giuseppe G. G. Manzardo, Martin Karpf, André S. Dreiding

Journal:

Helvetica Chimica Acta

Year:

1986

File:

PDF, 764 KB

1986

28

The Synthesis of Trimethylcyclopentane-carboxylic Acids

Bogdan Šolaja, Joan Huguet, Martin Karpf, André S. Dreiding

Journal:

Helvetica Chimica Acta

Year:

1986

Language:

english

File:

PDF, 590 KB

english, 1986

29

Butanolide und Butenolide durch intramolekulare En-Reaktion bei der Thermolyse von Propargyl-propiolaten

Vanda Bilinski, Martin Karpf, André S. Dreiding

Journal:

Helvetica Chimica Acta

Year:

1986

File:

PDF, 478 KB

1986

30

Application of the α-alkynone cyclization : synthesis of rac-modhephene

Martin Karpf, André S. Dreiding

Journal:

Tetrahedron Letters

Year:

1980

Language:

english

File:

PDF, 103 KB

english, 1980

31

Synthesis of ficisterol - the first natural sterol with 23-thyl substitution

Martin Karpf, Carl Djerassi

Journal:

Tetrahedron Letters

Year:

1980

Language:

english

File:

PDF, 214 KB

english, 1980

32

The flow thermolyses of 1-isobutenyl alkynyl- and 2-methylphenyl alkynyl ketones. Synthesis of methylenomycin B

Manuel Roller, Martin Karpf, André S. Dreiding

Journal:

Tetrahedron Letters

Year:

1986

Language:

english

File:

PDF, 202 KB

english, 1986

33

The acylation of acetylenes with β, γ-unsaturated acid chlorides: a new sysnthesis of 5,5-disubstituted 2-cyclopentenones

Journal:

Tetrahedron Letters

Year:

1982

Language:

english

File:

PDF, 251 KB

english, 1982

34

Synthesis of a stereoisomer of ptychanolide

Joan Huguet, Martin Karpf, André S. Dreiding

Journal:

Tetrahedron Letters

Year:

1983

Language:

english

File:

PDF, 239 KB

english, 1983

35

The synthesis of (±)-isoptychanolide by application of the α-alkynone cyclisation

Bogdan S̄olaja, Joan Huguet, Martin Karpf, André S. Dreiding

Journal:

Year:

1987

Language:

english

File:

PDF, 803 KB

english, 1987

36

Observation of Pseudorotamers of Two Unconstrained Wittig Intermediates, (3RS,4SR)- and (3RS,4RS)-4-Cyclohexyl-2-ethyl-3,4- dimethyl-2,2-diphenyl-1,2λ5-oxaphosphetane, by Dynamic 31P NMR Spectroscopy: Line-Shape Analyses, Conformations, and Decomposition Kinetics

Bangerter, Felix, Karpf, Martin, Meier, Lukas A., Rys, Paul, Skrabal, Peter

Journal:

Journal of the American Chemical Society

Year:

1998

Language:

english

File:

PDF, 86 KB

english, 1998

37

The Synthetic Development of the Anti-Influenza Neuraminidase Inhibitor Oseltamivir Phosphate (Tamiflu®): A Challenge for Synthesis & Process Research

Zutter, Ulrich, Abrecht, Stefan, Harrington, Peter, Iding, Hans, Karpf, Martin, Trussardi, René, Wirz, Beat

Journal:

CHIMIA International Journal for Chemistry

Year:

2004

Language:

english

File:

PDF, 625 KB

english, 2004

38

PMS65 Quality of Life in Patients with Rheumatoid Arthritis in Biological Therapy in Colombia

R.M. Romero martin, A.N. Alvis Nelson, L.T.M.C. La Torre Maria Constanza, K.E. Karpf Elizabeth

Journal:

Value in Health

Year:

2012

Language:

english

File:

PDF, 57 KB

english, 2012

39

Vascular Endothelial Expression of Indoleamine 2,3-Dioxygenase 1 Forms a Positive Gradient towards the Feto-Maternal Interface

Blaschitz, Astrid, Gauster, Martin, Fuchs, Dietmar, Lang, Ingrid, Maschke, Petra, Ulrich, Daniela, Karpf, Eva, Takikawa, Osamu, Schimek, Michael G., Dohr, Gottfried, Sedlmayr, Peter, Chatenoud, Lucien

Journal:

Year:

2011

Language:

english

File:

PDF, 1.32 MB

english, 2011

40

New, Azide-Free Transformation of Epoxides into 1,2-Diamino Compounds: Synthesis of the Anti-Influenza Neuraminidase Inhibitor Oseltamivir Phosphate (Tamiflu)

Karpf, Martin, Trussardi, René

Journal:

Journal of Organic Chemistry

Year:

2001

Language:

english

File:

PDF, 113 KB

english, 2001

41

PIH20 Cost Minimization Analysis of the Dienogest Use in Patients with Endometris in Colombia and Argentina

Romero Martin, R.M., Alvis Nelson, A.N., Alfonso Camilo, A.C., Karpf Elizabeth, K.E., Upegui Angie, U.A.

Journal:

Value in Health

Year:

2012

Language:

english

File:

PDF, 57 KB

english, 2012

42

Stereospecific transformation of 2,2-dimethylcyclobutanols into optically active 1,2-cis-disubstituted cyclopropanes

Karpf, Martin, Djerassi, Carl

Journal:

Journal of the American Chemical Society

Year:

1981

Language:

english

File:

PDF, 702 KB

english, 1981

43

The Medical Evaluation of Elderly Patients With Major Depression

Sweer, L., Martin, D. C., Ladd, R. A., Miller, J. K., Karpf, M.

Journal:

Journal of Gerontology

Year:

1988

Language:

english

File:

PDF, 785 KB

english, 1988

44

With Asymmetric Hydrogenation Towards a New, Enantioselective Synthesis of Orlistat

Birk, Rolf, Karpf, Martin, Püntener, Kurt, Scalone, Michelangelo, Schwindt, Mark, Zutter, Ulrich

Journal:

CHIMIA International Journal for Chemistry

Year:

2006

Language:

english

File:

PDF, 484 KB

english, 2006

45

The Synthetic-Technical Development of Oseltamivir Phosphate Tamiflu™: A Race against Time

Abrecht, Stefan, Federspiel, Muriel Cordon, Estermann, Heinrich, Fischer, Rolf, Karpf, Martin, Mair, Hans-Jürgen, Oberhauser, Thomas, Rimmler, Gösta, Trussardi, René, Zutter, Ulrich

Journal:

CHIMIA International Journal for Chemistry

Year:

2007

Language:

english

File:

PDF, 832 KB

english, 2007

46

Tryptophan dilates preconstricted chorionic arteries and endothelial indoleamine 2,3-dioxygenase-1 is deficient in intrauterine growth restriction and preeclampsia

Laguardia, Pablo Zardoya, Blaschitz, Astrid, Frank, Sasa, Lang-Olip, Ingrid, Gauster, Martin, Haeusler, Martin, Cervar-Zivkovic, Mila, Karpf, Eva, Sedlmayr, Peter

Journal:

Year:

2015

Language:

english

File:

PDF, 47 KB

english, 2015

47

Studying Chemistry at the University of Zurich in the Sixties and Seventies of the Last Century: A Personal View

Journal:

CHIMIA International Journal for Chemistry

Year:

2008

Language:

english

File:

PDF, 277 KB

english, 2008

48

Community-Based Geriatric Assessment

Martin, David C., Morycz, Richard K., McDowell, B. Joan, Snustad, Diane, Karpf, Michael

Journal:

Journal of the American Geriatrics Society

Year:

1985

Language:

english

File:

PDF, 518 KB

english, 1985

49

A novel tryptophan-based mechanism regulating the tonus of the placental vascular bed is impaired in intrauterine growth restriction and preeclampsia

Zardoya-Laguardia, Pablo, Blaschitz, Astrid, Hirschmugl, Birgit, Lang, Ingrid, Gauster, Martin, Häusler, Martin, Cervar-Zivkovic, Mila, Karpf, Eva, Wadsack, Christian, Frank, Saša, Sedlmayr, Peter

Journal:

Year:

2016

Language:

english

File:

PDF, 49 KB

english, 2016

50

Targeted enrichment sequencing in two midterm pregnancies with severe abnormalities on ultrasound

Kroisel, Peter Michael, Häusler, Martin, Klaritsch, Phillip, Karpf, Eva, Zebedin, Doris, Tiran, Beate, Pertl, Barbara, Wagner, Klaus

Journal:

Year:

2017

Language:

english

File:

PDF, 119 KB

english, 2017